C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) C07K 14/33 (2006.01) C07K 14/47 (2006.01) C07K 14/475 (2006.01) C07K 14/52 (2006.01) C07K 14/575 (2006.01) C07K 19/00 (2006.01) C12N 9/00 (2006.01) C12N 9/52 (2006.01) C12N 15/12 (2006.01) C12N 15/31 (2006.01) C12N 15/55 (2006.01) C12P 21/02 (2006.01)
Patent
CA 2601537
The specification discloses modified Clostridial toxins comprising a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain and an enhanced Clostridial toxin binding domain; polynucleotide molecules encoding such modified Clostridial toxins; and method of producing such modified Clostridial toxins.
L'invention concerne des toxines clostridiales modifiées comprenant un domaine enzymatique de toxine clostridiale, un domaine de translocation de toxine clostridiale et un domaine de liaison de toxine clostridiale amélioré. L'invention concerne également des molécules polynucléotidiques codant ces toxines clostridiales modifiées, et une méthode de production de telles toxines clostridiales modifiées.
Aoki Kei R.
Fernandez-Salas Ester
Francis Joseph
Gilmore Marcella A.
Li Shengwen
Allergan Inc.
Gowling Lafleur Henderson Llp
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