C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) C07K 14/33 (2006.01) C07K 14/50 (2006.01) C07K 19/00 (2006.01) C12N 9/00 (2006.01) C12N 9/52 (2006.01) C12N 15/18 (2006.01) C12N 15/31 (2006.01) C12N 15/55 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01)
Patent
CA 2601577
The specification discloses modified Clostridial toxins comprising a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain and an enhanced Clostridial toxin binding domain; polynucleotide molecules encoding such modified Clostridial toxins; and method of producing such modified Clostridial toxins.
L'invention porte sur des toxines de clostridiose modifiées contenant un domaine enzymatique de toxine de clostridiose, un domaine de translocation de toxine de clostridiose ainsi qu'un domaine de liaison de toxine de clostridiose ; sur des molécules de polynucléotide qui codent ces toxines de clostridiose modifiées ; ainsi que sur un procédé de fabrication de ces toxines de clostridiose modifiées.
Aoki Kei R.
Fernandez-Salas Ester
Francis Joseph
Gilmore Marcella A.
Li Shengwen
Allergan Inc.
Gowling Lafleur Henderson Llp
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