C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01) A61K 38/17 (2006.01) A61P 37/02 (2006.01)
Patent
CA 2720617
The present invention relates to isolated Cpn10 polypeptides possessing an increased affinity for a PRR ligand compared to Ala Cpn10 polypeptide. In a further embodiment, the present invention also relates to modified chaperonin 10 polypeptides, and to nucleic acids encoding the same and to compositions comprising such polypeptides and uses thereof.
La présente invention porte sur des polypeptides Cpn10 isolés possédant une affinité accrue pour un ligand de récepteur PRR par comparaison avec un polypeptide Ala Cpn10. Dans un autre mode de réalisation, la présente invention porte également sur des polypeptides chaperonine 10 et sur des acides nucléiques codant ceux-ci et sur des compositions comprenant de tels polypeptides et sur les utilisations de ces compositions.
Brown Richard James
de Bakker Christopher John
Elizabeth Stok Jeanette
Howard Christopher Bruce
James Andrew Leigh
Cbio Limited
Smart & Biggar
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