Modified gangliosides and the functional derivatives thereof

Details Modified gangliosides and the functional derivatives thereof Modified gangliosides and the functional derivatives thereof

C - Chemistry, Metallurgy

07

H

167/195, 167/199

C07H 5/06 (2006.01) A61K 31/70 (2006.01) C07H 15/10 (2006.01) C07J 9/00 (2006.01)

Patent

CA 2029974

ABSTRACT OF THE DISCLOSURE N-acyl-N,N'-di-lysogangliosides, N'-acyl-N,N'-di- lysogangliosides and N,N'-diacyl-N,N'-di- lysogangliosides, in which the acyl groups are derived from an organic acid of the aliphatic, aromatic, araliphatic, alicyclic or heterocyclic series and in which at least one of the two acyl groups is not aliphatic, and their preparation are disclosed. Also disclosed is the preparation of the esters, inner esters, amides and hydroxy peracylates of these compounds and salts thereof. These compounds are useful in the treatment of pathologies of the central and peripheral nervous systems.

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