Modified glucocorticoid receptors, glucocorticoid...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 38/17 (2006.01) C07K 14/72 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2269642

The present invention provides modified proteins of steroid hormone receptors. These mutated proteins are useful as gene medicines. In particular, these mutated proteins are useful for regulating expression of genes in gene therapy. In addition, the present invention provides plasmids encoding for the desired mutated steroid hormone receptor proteins, as well as cells transfected with those plasmids.

L'invention concerne des protéines modifiées de récepteurs pour les hormones stéroïdes. Ces protéines mutées sont utiles en tant que médicaments géniques. Elles sont particulièrement utiles pour la régulation de l'expression de gènes dans la thérapie génique. De plus, l'invention porte sur des plasmides codant pour les protéines de récepteurs pour les hormones stéroïdes mutées voulues ainsi que sur des cellules transfectées au moyen de ces plasmides.

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