Modified gp100 and uses thereof

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/47 (2006.01) A61K 35/76 (2006.01) A61K 39/00 (2006.01) A61K 39/12 (2006.01) A61K 39/275 (2006.01) A61P 31/14 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01) C12N 7/01 (2006.01) C12N 15/12 (2006.01) C12N 15/86 (2006.01) C12N 15/863 (2006.01)

Patent

CA 2721011

A gp100 molecule useful in modulating the immune system is described. In particular what is described is a nucleotide sequence for a gp100 which has been modified so as to be useful in modulating the immune system. The isolated nucleic acid sequence is described and referred to as gp100M. The corresponding protein, referred to as gp100M, is also described. Applications of the molecules as vaccines are described.

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