Modified human thymic stromal lymphopoietin

Details Modified human thymic stromal lymphopoietin Modified human thymic stromal lymphopoietin

C - Chemistry, Metallurgy

12

N

C12N 15/24 (2006.01) A61K 31/7088 (2006.01) A61K 38/18 (2006.01) A61K 38/20 (2006.01) A61K 48/00 (2006.01) C07K 14/475 (2006.01) C07K 14/54 (2006.01) C07K 16/22 (2006.01) C07K 16/24 (2006.01) C07K 19/00 (2006.01) C12N 5/10 (2006.01) C12N 15/18 (2006.01) C12N 15/62 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2454578

Modified, furin resistant human TSLP polypeptides and polynucleotides encoding the modified human TSLP polypeptides are provided. Pharmaceutical compositions, B and T cell activation agents, assays and methods of use are also described.

L'invention concerne des polypeptides TSLP humains modifiés, résistant à la furine, et des polynucléotides codant ces polypeptides. L'invention concerne également des compositions pharmaceutiques, des activateurs de lymphocytes B et T, des tests, et des procédés d'utilisation correspondants.

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