Modified lecithin-cholesterol acyltransferase enzymes

Details Modified lecithin-cholesterol acyltransferase enzymes Modified lecithin-cholesterol acyltransferase enzymes

C - Chemistry, Metallurgy

12

N

C12N 9/10 (2006.01) A61K 38/45 (2006.01)

Patent

CA 2694590

The invention provides compounds, pharmaceutical compositions and methods for treating atherosclerosis, coronary heart disease, thrombosis, and for decreasing or prevention of accumulation of cholesterol in a subject by modifying LCAT polypeptide.

L'invention concerne des composés, des compositions pharmaceutiques et des procédés pour traiter l'athérosclérose, une maladie coronarienne, une thrombose et pour diminuer ou empêcher l'accumulation de cholestérol chez un sujet par modification du polypeptide LCAT

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