C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 31/711 (2006.01) A61K 39/102 (2006.01) C07K 14/285 (2006.01) C07K 16/12 (2006.01) C12N 15/62 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2394357
The present invention provides nucleic acid sequences encoding a modified leukotoxin protein, wherein the modification comprises the removal of nucleic acid sequences encoding amino acids within hydrophobic transmembrane domains of full length leukotoxin protein, preferably from Mannheimia haemolytica. The modified leukotoxin proteins are useful in vaccine compositions effective against Mannheimia haemolytica in animals.
La présente invention concerne des séquences d'acide nucléique codant pour une leucotoxine modifiée, dans laquelle les modifications comprennent la suppression de séquences d'acides nucléiques codant pour des acides aminés au sein des domaines transmembranaires hydrophobes de la leucotoxine pleine longueur, de préférence de Mannheimia haemolytica. Les leucotoxines modifiées sont utiles dans la formulation de vaccins efficaces contre Mannheimia haemolytica chez les animaux.
Hodgins Doug
Lee Raymond W. H.
Lo Reggie Y. C.
Shewen Patricia E.
Strommer Judith N.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
University Of Guelph
LandOfFree
Modified leukotoxin gene and protein does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Modified leukotoxin gene and protein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Modified leukotoxin gene and protein will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1544757