Modified ligands of calcium-dependent binding proteins

Details Modified ligands of calcium-dependent binding proteins Modified ligands of calcium-dependent binding proteins

C - Chemistry, Metallurgy

12

N

C12N 9/12 (2006.01) A61K 38/45 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 51/08 (2006.01) C07K 14/435 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2250921

The present invention relates to ligands capable of binding a calcium dependent binding protein, that comprise an amino acid sequence corresponding to that of a wild type ligand for the calcium dependent binding protein, with a modification which results in enhanced affinity of the ligand for the calcium dependent binding protein.

L'invention concerne des ligands capables de lier une protéine de liaison dépendante du calcium, qui contiennent une séquence d'acides aminés correspondant à celle du ligand de type sauvage pour ladite protéine, avec une modification augmentant l'affinité du ligand pour la protéine de liaison dépendante du calcium.

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