Modified neurotoxin derived from naja genus snake venom

Details Modified neurotoxin derived from naja genus snake venom Modified neurotoxin derived from naja genus snake venom

A - Human Necessities

61

K

167/104

A61K 39/38 (2006.01) A61K 35/58 (2006.01)

Patent

CA 1108533

ABSTRACT OF THE DISCLOSURE The present invention relates to a composition, a process of production thereof, and a method for treat- ment of neurological diseases, and especially to the treat- ment of such diseases as amyotropic lateral sclerosis, by administering detoxified but neurotropically active modified snake venom neurotoxin composition derived from the venom of the Naja genus, where the composition exhibits at least a 30% inhibition of viral plaques in the Semliki Forest virus test and a bioassay shows the composition to be atoxic.

301417

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