C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/00 (2006.01) A61K 31/70 (2006.01) A61K 31/7052 (2006.01) A61K 31/7084 (2006.01) A61K 31/7088 (2006.01) C07H 19/044 (2006.01) C07H 19/14 (2006.01) C07H 23/00 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01)
Patent
CA 2162075
The invention relates to novel modified oligonucleotides which possess at least one substituted 7-deazapurine base and form more stable hybdridization complexes with nucleic acids; to processes for their preparation and to their use as inhibitors of gene expression, as probes for detecting nucleic acids, as aids in molecular biology and as pharmaceuticals or diagnostic agents.
Seela Frank
Thomas Horst
Aventis Pharma Deutschland Gmbh
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
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