Modified oncolytic viruses

Details Modified oncolytic viruses Modified oncolytic viruses

C - Chemistry, Metallurgy

12

N

C12N 15/41 (2006.01) C12N 9/50 (2006.01)

Patent

CA 2559055

The present invention provides an isolated selected Picornavirus capable of lytically infecting or inducing apoptosis in a cell substantially in the absence of intercellular adhesion molecule-1 (ICAM-1), and methods for treating subjects.

La présente invention a trait à un Picornavirus sélectionné isolé apte à l'infection lytique ou menant à l'apoptose dans une cellule sensiblement en l'absence de molécule d'adhésion intercellulaire 1(ICAM-1), et à des procédé de traitement de sujets.

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