Modified phytases

Details Modified phytases Modified phytases

C - Chemistry, Metallurgy

12

N

C12N 15/55 (2006.01) A23K 1/165 (2006.01) A23L 1/03 (2006.01) C12N 9/16 (2006.01)

Patent

CA 2231948

Phytases (myo-inositol hexakisphosphate phosphohydrolases; EC 3.1.3.8) are enzymes that hydrolyze phytate (myo-inositol hexakisphosphate) to myo-inositol and inorganic phosphate, and are known to be valuable feed additives. A phytase which has been modified in a way that its activity is more favourable than that of the non- modified phytase is described. More specifically such a modified phytase is characterized in that the amino acid sequence of the non-modified phytase has been changed by deletion, substitution and/or addition of one ore more amino acids.

Les phytases (myo-inositol hexakisphosphate phosphohydrolases; EC 3.1.3.8) sont des enzymes qui hydrolysent le phytate (myo-inositol hexakisphosphate) en myo-inositol et en phosphate minéral, et sont connues pour leur grande valeur comme additifs alimentaires. L'invention décrit une phytase qui a été modifiée de telle façon que son activité soit plus avantageuse que celle de la phytase non modifiée. Plus spécifiquement, une phytase modifiée de ce type est caractérisée par le fait que la séquence d'acides aminés de la phytase non modifiée a été changée par délétion, substitution et (ou) addition d'un ou de plusieurs acides aminés.

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