A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/385 (2006.01) C07K 14/015 (2006.01) C07K 16/08 (2006.01) C07K 16/12 (2006.01) C07K 16/26 (2006.01) C07K 16/28 (2006.01) C07K 16/42 (2006.01)
Patent
CA 2387629
The present invention relates to modulating the nature and/or level of an immune response to a molecule. In particular, the invention relates to effecting an increase in the TH1 immune response to molecules such as, but not limited to, antigens or immunogens. The invention also relates to reducing a TH2 immune response to molecules. More particularly, the invention relates to altering the level of TH1- and TH2-associated immunoglobulins, the level of proliferation of TH1- and TH2-associated cytokines, and the level of proliferation of TH1 and TH2 cells.
La présente invention concerne la modulation de la nature et/ou du niveau d'une réponse immunitaire à une molécule. Elle concerne en particulier une méthode pouvant augmenter la réponse immunitaire de TH1 à des molécules, telles que, mais pas exclusivement, des antigènes ou des immunogènes. L'invention concerne en outre une méthode permettant de diminuer la réponse immunitaire de TH2 à des molécules. Plus particulièrement, l'invention concerne une méthode permettant de modifier le niveau d'immunoglobulines associées à TH1 et TH2, le niveau de prolifération de cytokines associées à TH1 et TH2, et le niveau de prolifération de cellules TH1 et TH2.
Smart & Biggar
The Dow Chemical Company
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