Modified protein kinase a-specific oligonucleotides and...

Details Modified protein kinase a-specific oligonucleotides and... Modified protein kinase a-specific oligonucleotides and...

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) A61K 31/70 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2232724

Disclosed are synthetic, modified oligonucleotides complementary to, and capable of down-regulating the expression of, nucleic acid encoding protein kinase A subunit RI.alpha.. The modified oligonucleotides have from about 15 to about 30 nucleotides and are hybrid, inverted hybrid, or inverted chimeric oligonucleotides. Also disclosed are therapeutic compositions containing such oligonucleotides and methods of using the same.

L'invention porte sur des oligonucléotides de synthèse modifiés complémentaires de la sous-unité RI¿.alpha.? de la protéine kinase A codant pour un acide nucléique et capable d'en réduire l'expression. Lesdits oligonucléotides, au nombre de 15 à 30, sont du type hybride, hybride inversé ou chimérique inversé. L'invention porte également sur des compositions thérapeutiques les contenant et leurs modes d'utilisation.

Affiliated with

Also associated with

Rating

Modified protein kinase a-specific oligonucleotides and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Modified protein kinase a-specific oligonucleotides and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Modified protein kinase a-specific oligonucleotides and... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1685082