Modified proteinase inhibitors

Details Modified proteinase inhibitors Modified proteinase inhibitors

C - Chemistry, Metallurgy

12

N

C12N 15/29 (2006.01) A01H 5/00 (2006.01) A01N 37/18 (2006.01) A01N 37/46 (2006.01) A01N 61/00 (2006.01) A61K 38/55 (2006.01) C07K 14/81 (2006.01) C07K 19/00 (2006.01) C12N 15/15 (2006.01) C12N 15/62 (2006.01) C12N 15/82 (2006.01)

Patent

CA 2205356

The invention relates to proteinase inhibitors and in particular cystatins which have been modified so as to enhance their effective or synthetically manufactured counterparts. The modification including either site-directed alterations in the structure of the protein and/or the production of hybrid molecules.

L'invention concerne des inhibiteurs de protéases et en particulier des cystatines qui ont été modifiées pour augmenter leur efficacité, ou leurs équivalents réalisés par synthèse. Ces modifications peuvent consister en des altérations visant des sites de la structure de la protéine et/ou aboutissant à des molécules hybrides.

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