Modified proteins

Details Modified proteins Modified proteins

C - Chemistry, Metallurgy

12

N

167/103.05, 530/

C12N 15/15 (2006.01) A61K 38/58 (2006.01) C07K 14/815 (2006.01) C12N 15/81 (2006.01) C12N 15/82 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1339105

Novel eglin mutants that differ from the natural eglins B and C by the replacement of one, two or three amino acids in the region of the active centre (amino acids 45 and 46, Leu-Asp) by other amino acids are provided. The mutants, which can be produced by recombinant genetic engineering, have valuable pharmacological properties.

592686

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