Modified psma ligands and uses related thereto

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

C07F 9/72 (2006.01) A61K 31/66 (2006.01) A61K 31/69 (2006.01) C07C 229/00 (2006.01) C07F 5/02 (2006.01) C07F 9/28 (2006.01) C07F 9/30 (2006.01) C07F 9/32 (2006.01)

Patent

CA 2436408

The instant invention provides reagents and methods for diagnosis, detection and treatment of cancers (for example, prostate cancers). In particular, the invention provides methods to generate various functionalized PSMA ligands, and their uses in diagnosis, detection, imaging, and treatment of prostate cancers, especially those overexpressing PSMA.

La présente invention concerne des réactifs et des procédés permettant de diagnostiquer, détecter et traiter les cancers (par exemple, les cancers de la prostate). En particulier, la présente invention traite de procédés pour générer divers ligands de la PSMA fonctionnalisés, et leur utilisation pour diagnostiquer, détecter, effectuer une imagerie et traiter les cancers de la prostate, en particulier, ceux surexprimant la PSMA.

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