A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 51/10 (2006.01) A61K 39/44 (2006.01) A61K 47/48 (2006.01) C07K 16/00 (2006.01)
Patent
CA 2200482
PEG-modified-Tc-99m-radiolabeled antibody fragments are useful for radioimmunodetection of tumors and infectious lesions and display striking reductions in renal uptake and retention of radioisotope compared to non-PEG- modified fragments.
L'invention concerne des fragments d'anticorps Tc-99m radio-marqués et modifiés en polyéthylène glycol utilisés pour détecter par la méthode radioimmunologique des tumeurs et des lésions de nature infectieuse. Ces fragments permettent de réduire de manière significative l'absorption rénale et la rétention d'isotopes radioactifs par rapport à des fragments non modifiés en polyéthylène glycol.
Griffiths Gary L.
Hansen Hans J.
Karacay Habibe
Immunomedics Inc.
Smart & Biggar
LandOfFree
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