Modified release...

A - Human Necessities – 61 – K

Patent

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A61K 31/40 (2006.01) A61K 9/22 (2006.01) A61K 9/24 (2006.01)

Patent

CA 2610422

The subject invention provides a pharmaceutical tablet formulation comprising per unit dosage form e.g. per tablet the following ingredients: (a) a compound as an active ingredient, wherein the compound has a formula: [Chemical formula should be inserted here as it appears on Abstract in paper form] wherein R is substituted adamantyl and n is an integer from 0 to 3 or a pharmaceutically acceptable salt thereof; (b) a hydroxypropyl methylcellulose with an apparent viscosity of 80,000 cP to 120,000 cP (nominal value 100,000 cP) when present in a 1% solution; (c) a microcrystalline cellulose; and (d) a magnesium stearate

L'invention concerne une formulation de comprimé pharmaceutique comprenant, par forme dosifiée unitaire, par exemple par comprimé, les ingrédients suivants: (a) un composés servant de principe actif, le composé susmentionné présentant la formule (I). Dans la formule de l'invention, R désigne de l'adamantyle substitué et n désigne un nombre entier compris entre 0 et 3, ou un sel pharmaceutiquement acceptable de celui-ci; (b) une méthylcellulose d'hydroxypropyle présentant une viscosité apparente comprise entre 80000 cP et 120000 cP (valeur nominale 100000 cP) lorsqu'elle est présente dans un solution à 1 %; (c) une cellulose microcrystalline; et (d) un stéarate de magnésium.

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Profile ID: LFCA-PAI-O-2052011

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