Modified release ciprofloxacin compositions

Details Modified release ciprofloxacin compositions Modified release ciprofloxacin compositions

A - Human Necessities

61

K

A61K 31/496 (2006.01) A61K 9/20 (2006.01) A61K 9/24 (2006.01) A61J 3/10 (2006.01)

Patent

CA 2589551

Controlled release tablets comprising ciprofloxacin, with hardness and friability of the said tablets ranges between 10 to 70 kiloponds and less than 2% respectively, the compositions releasing at least 80 percent of the total amount of the ciprofloxacin into a pH 1.2 aqueous dissolution medium within about 1 hour.

L'invention se rapporte à des comprimés à libération contrôlée comportant de la ciprofloxacine, lesdits comprimés présentant une dureté comprise entre 10 et 70 kilogrammes-force et une friabilité inférieure à 2 %, ces compositions libérant au moins 80 % de la quantité totale de la ciprofloxacine dans un milieu de dissolution aqueux à un pH de 1,2 en approximativement 1 heure.

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