Modified release dosage form

Details Modified release dosage form Modified release dosage form

A - Human Necessities

61

K

A61K 9/20 (2006.01) A61K 9/00 (2006.01) A61K 9/28 (2006.01) A61K 9/30 (2006.01) A61K 9/34 (2006.01) A61K 9/36 (2006.01)

Patent

CA 2500312

A modified release dosage form comprising at least one active ingredient and at least two cores surrounded by a shell is provided. The shell comprises at least one opening and provides for modified release of active ingredient upon contacting of the dosage form with a liquid medium. At least one of the cores is distal from the opening. In a preferred embodiment, the dosage form has a pulsatile release profile.

L'invention porte sur une forme galénique à libération modifiée comprenant au moins un ingrédient actif et au moins deux noyaux entourés d'une capsule. La capsule comprend au moins un orifice et assure la libération modifiée d'un ingrédient actif lors de la mise en contact de la forme galénique avec un milieu liquide. Au moins un des noyaux est distal de l'orifice. Selon une réalisation préférée, la forme galénique a un profil de libération pulsatile.

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