Modified release famciclovir pharmaceutical compositions

Details Modified release famciclovir pharmaceutical compositions Modified release famciclovir pharmaceutical compositions

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 9/22 (2006.01) A61K 31/52 (2006.01)

Patent

CA 2607626

A modified release pharmaceutical composition of famciclovir contains at least 60% by weight famciclovir with at least 5% by weight of a release retardant. Particularly useful as a release retardant include polymers, especially a mixture of polyvinyl acetate and polyvinylpyrrolidone. A method of making such pharmaceutical compositions using a extruder and a granulation method is particularly useful.

Composition pharmaceutique de famciclovir à libération modifiée contenant au moins 60 % en poids de famciclovir dont au moins 5 % en poids consiste en un retardateur de libération. Un retardateur de libération particulièrement utile est constitué de polymères, particulièrement, un mélange d'acétate de polyvinyle et de polyvinylpyrrolidone. Méthode efficace de préparation de ces compositions pharmaceutiques au moyen d'une extrudeuse et d'un processus de granulation.

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