Modified release ibuprofen solid oral dosage form

Details Modified release ibuprofen solid oral dosage form Modified release ibuprofen solid oral dosage form

A - Human Necessities

61

K

A61K 9/22 (2006.01) A61K 9/16 (2006.01) A61K 9/26 (2006.01) A61K 31/192 (2006.01)

Patent

CA 2670887

The present invention is a solid dosage form for oral administration of ibuprofen comprising a modified release formulation of ibuprofen which provides an immediate burst effect and thereafter a sustained release of sufficient ibuprofen to maintain blood levels at least 6.4 µg/ml over an extended period of at least 8 hours following administering of a single dose.

La présente invention concerne une forme pharmaceutique solide d'ibuprofène destinée à une administration orale. Ladite forme pharmaceutique comprend une formulation d'ibuprofène à libération modifiée qui fournit un effet de décharge immédiat. Ladite forme pharmaceutique contient également une quantité d'ibuprofène à libération prolongée en quantité suffisante pour maintenir les niveaux sanguins à au moins 6,4 µg/ml, au cours d'une période prolongée d'au moins 8 heures suivant l'administration d'une dose unique.

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