Modified-release preparations containing oxcarbazepine and...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/55 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/50 (2006.01) A61K 47/32 (2006.01) A61K 47/34 (2006.01) A61K 47/36 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2597740

Controlled-release preparations of oxcarbazepine and derivatives thereof for once-a-day administration are disclosed. The inventive compositions comprise solubility- and/or release enhancing agents to provide tailored drug release profiles, preferably sigmoidal release profiles. Methods of treatment comprising the inventive compositions are also disclosed.

La présente invention décrit des préparations à libération contrôlée d'oxcarbazépine et de dérivés de celle-ci pour administration une fois par jour. Les compositions inventives comprennent des agents améliorant la solubilité et/ou la libération pour générer des profils de libération de médicaments sur mesure, de préférence des profils de libération sigmoïdes. Elle décrit également des méthodes de traitement comprenant les compositions inventives.

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