Modified-release tablet of bupropion hydrochloride

Details Modified-release tablet of bupropion hydrochloride Modified-release tablet of bupropion hydrochloride

A - Human Necessities

61

K

A61K 31/137 (2006.01) A61K 9/22 (2006.01) A61K 9/24 (2006.01) A61P 25/24 (2006.01)

Patent

CA 2524300

A modified-release tablet of bupropion hydrochloride comprising (i) a core comprising an effective amount of bupropion hydrochloride, a binder, a lubricant; and (ii) a control releasing coat surrounding said core; and (iii) a moisture barrier surrounding said control releasing coat, wherein the modified-release tablet is bioequivalent to Wellbutrin© or Zyban®/Wellbutrin®SR tablets.

L'invention concerne un comprimé de chlorhydrate de bupropion à libération modifiée comprenant (i) un noyau renfermant une dose efficace de chlorhydrate de bupropion, un liant et un lubrifiant, (ii) un enrobage à libération progressive entourant ce noyau, et (iii) une barrière d'étanchéité à l'humidité entourant l'enrobage à libération progressive, ce comprimé à libération modifiée étant bioéquivalent aux comprimés Wellbutrin© ou Zyban©/Wellbutrin©SR.

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