Modified rsv f proteins and methods of their use

Details Modified rsv f proteins and methods of their use Modified rsv f proteins and methods of their use

C - Chemistry, Metallurgy

07

K

C07K 19/00 (2006.01) A61K 39/155 (2006.01) A61P 31/14 (2006.01) A61P 37/04 (2006.01) C07K 14/135 (2006.01) C07K 17/04 (2006.01) C12N 7/01 (2006.01) C12N 15/00 (2006.01) C12N 15/45 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2746228

The present invention is generally related to modified or mutated respiratory syncytial virus fusion (F) proteins and methods for making and using them, including immunogenic compositions such as vaccines for the treatment and/or prevention of RSV infection.

La présente invention concerne de façon générale des protéines de fusion (F) de virus respiratoire syncytial modifiées ou mutées, ainsi que leurs méthodes de fabrication et d'utilisation, y compris les compositions immunogènes comme les vaccins dans le traitement prophylactique et/ou thérapeutique d'une infection par le VRS.

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