Modified sialyl lewis a compounds

Details Modified sialyl lewis a compounds Modified sialyl lewis a compounds

C - Chemistry, Metallurgy

12

P

C12P 19/26 (2006.01) A61K 31/70 (2006.01) A61K 38/02 (2006.01) A61K 39/385 (2006.01) C07H 3/06 (2006.01) C07H 13/04 (2006.01) C07H 15/04 (2006.01) C07H 19/10 (2006.01) C07H 19/20 (2006.01) C07K 2/00 (2006.01) C12P 19/44 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2110582

The present invention is drawn to methods for the synthesis of Lewis a derivatives modified at the C-2 and/or C-6 position of G1cNAc employing chemoenzymatic synthesis. The derivatives find use in the treatment and prevention of diseases.

Cette invention concerne des procédés permettant d'effectuer la synthèse de dérivés de Lewisa modifiés au niveau de la position C-2 et/ou C-6 de GlcNAc à l'aide de la synthèse chimio-enzymatique. Ces dérivés peuvent être utilisés pour traiter et empêcher l'apparition des maladies.

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