Modified spider silk proteins

Details Modified spider silk proteins Modified spider silk proteins

C - Chemistry, Metallurgy

07

K

C07K 14/435 (2006.01) C12N 15/12 (2006.01)

Patent

CA 2619917

The present invention is directed to a method of modifying a spider silk protein and a spider silk protein obtainable by said method. The invention further pertains to a nucleic acid sequence coding for a modified spider silk protein, a vector containing said sequences and host cells transformed with this vector. The invention furthermore is directed to a pharmaceutical or cosmetical composition containing a modified spider silk protein as defined herein and the use of said modified sequences in various fields, in particular in the fields of medicine, cosmetics and technical applications.

La présente invention concerne un procédé permettant de modifier une protéine de soie arachnéenne ainsi qu~une protéine de soie obtenue grâce à ce procédé. L~invention porte également sur une séquence d~acides nucléiques codant pour une protéine de soie arachnéenne modifiée, un vecteur contenant lesdites séquences et des cellules hôtes transformées à l~aide de ce vecteur. En outre, l~invention a trait à une composition pharmaceutique ou cosmétique contenant une protéine de soie arachnéenne modifiée, ci définie, et l~utilisation desdites séquences modifiées dans divers domaines, en particulier ceux de la médecine, des produits cosmétiques et des applications techniques.

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