Modified tgf-.beta. superfamily proteins

Details Modified tgf-.beta. superfamily proteins Modified tgf-.beta. superfamily proteins

C - Chemistry, Metallurgy

07

K

C07K 19/00 (2006.01) C07K 14/495 (2006.01) C07K 14/51 (2006.01)

Patent

CA 2657302

The invention provides modified TGF-.beta. family proteins having altered biological or biochemical properties, and methods for making them. Specific modified protein constructs include TGF- .beta. family member proteins that have N-terminal truncations, "latent" proteins, fusion proteins and heterodimers.

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