C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) A61K 38/16 (2006.01) A61K 38/17 (2006.01) A61P 35/00 (2006.01) C07K 14/15 (2006.01) C07K 14/16 (2006.01) C07K 14/78 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12N 15/48 (2006.01) C12N 15/88 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2390081
A vector particle having a surface protein which is modified to include a tumor targeting vasculature motif, or TVTM, peptide. Such peptides enable vector particles to be targeted to endothelial cells, and in particular to endothelial cells of the blood vessels of tumors, whereby agents which inhibit, prevent, or destroy the growth of such cells are delivered to the cells, thereby terminating the blood supply to a tumor.
L'invention concerne une particule vecteur assortie d'une protéine de surface qui a été modifiée pour recevoir un peptide à motif ciblant le réseau vasculaire tumoral (TVTM). Lesdits peptides permettant aux particules vecteurs de cibler les cellules endothéliales, notamment par les cellules endothéliales des vaisseaux sanguins des tumeurs. Les agents inhibant, empêchant ou anéantissant la croissance desdites cellules sont alors libérés au niveau des cellules, mettant ainsi un terme à l'alimentation en sang d'une tumeur.
Anderson W. French
Gordon Erlinda Maria
Hall Frederick L.
Fetherstonhaugh & Co.
University Of Southern California
LandOfFree
Modified viral surface proteins which bind to cells of tumor... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Modified viral surface proteins which bind to cells of tumor..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Modified viral surface proteins which bind to cells of tumor... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2070031