Modulated xenogeneic organ systems in an immunocompromised host

C - Chemistry – Metallurgy – 12 – N

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C12N 5/08 (2006.01) A61K 49/00 (2006.01) C12Q 1/18 (2006.01) G01N 33/50 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2048406

MODULATED XENOGENEIC ORGAN SYSTEMS IN AN IMMUNOCOMPROMISED HOST ABSTRACT OF THE DISCLOSURE Xenogeneic tissue is introduced into an immunocompromised host for interacting with agents and using such interaction for evaluating efficacy of drugs and vaccines, evaluating the effect of the various agents on specific tissues and the like. Particularly, drugs can be evaluated for their efficacy against a wide variety of pathogens which infect xenogeneic tissue, and agents can be evaluated for their effect on the xenogeneic immune system.

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