Modulating and/or detecting activation induced deaminase and...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/34 (2006.01) A61K 31/395 (2006.01) A61K 31/506 (2006.01) A61P 35/02 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2697887

A method for stratifying a subject, the method comprising: measuring the AID expression and/or activity in a first sample from the subject, and comparing the expression and/or activity in the first sample from the subject to a reference AID expression and/or activity, wherein an AID expression and/or activity in the first sample from the subject that is higher than the reference AID expression and/or activity is indicative that the subject would benefit from a treatment with at least one Heat Shock Protein 90 (Hsp90) inhibitor.

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