A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) A61K 31/00 (2006.01) A61K 31/7088 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) G01N 33/68 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2384537
Substances are provided that are capable of modulating angiogenesis mediated by Lmo2 or a functionally related polypeptide, which substance binds to Lmo2 and/or a functionally related polypeptide, or alters the expression of Lmo2 or a functionally related polypeptide in a cell. Assay methods are provided for identifying such substances.
L'invention concerne des substances pouvant moduler l'angiogénèse induite par Lmo2 ou par un polypeptide fonctionnellement apparenté. Cette substance se lie à Lmo2 et/ou audit polypeptide apparenté, ou bien elle modifie l'expression dans la cellule de Lmo2 ou d'un polypeptide fonctionnellement apparenté à Lmo2. L'invention concerne également des dosages permettant d'identifier de telles substances.
Rabbitts Terry
Yamada Yoshihiro
Mbm Intellectual Property Law Llp
Medical Research Council
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