Modulation of .beta.-catenin/tcf activated transcription

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 15/12 (2006.01) A61K 31/395 (2006.01) A61K 31/519 (2006.01) A61K 31/551 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C12N 15/09 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2537099

The present invention provides compounds and methods for modulating transcription activated by .beta.-catenin/TCF, such as the selective inhibition of genes targeted by the Wnt/.beta.-catenin pathway.

La présente invention concerne des composés et des procédés pour moduler la ?-caténine/TCF activée par la transcription, par exemple, l'inhibition sélective de gènes ciblés par la voie de Wnt/?-caténine.

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