Modulation of cell proliferative disorders by cyclic rgd

Details Modulation of cell proliferative disorders by cyclic rgd Modulation of cell proliferative disorders by cyclic rgd

A - Human Necessities

61

K

A61K 38/12 (2006.01) A61K 33/24 (2006.01) A61K 45/06 (2006.01) C07K 14/75 (2006.01) C07K 14/78 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2288680

Provided is use of a cyclic RGD sequences for the manufacture of a pharmaceutical composition to treat cell proliferative disorders. Such treatments include the inhibition and amelioration of cell proliferative disorders such as neuronal cell proliferative disorders, including glioblastoma, as well as prostate hyperplasia or neoplasia. Also provided are methods for identifying compounds useful in treating cell proliferative disorders associated with .alpha.v.beta.s, and methods for identifying cell proliferative disorders that are susceptible to treatment with cyclic RGD sequences.

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