Modulation of cholesteryl ester transfer protein (cetp)...

Details Modulation of cholesteryl ester transfer protein (cetp)... Modulation of cholesteryl ester transfer protein (cetp)...

C - Chemistry, Metallurgy

12

N

C12N 9/96 (2006.01) A61K 38/45 (2006.01) A61K 39/00 (2006.01) A61K 39/08 (2006.01) A61K 39/385 (2006.01) C07K 14/33 (2006.01) C07K 14/47 (2006.01) C12N 9/10 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2219795

This invention relates to peptides comprising a helper T cell epitope portion and a B cell epitope portion for eliciting an immune response against endogenous cholesteryl ester transfer protein (CETP) activity, to prevent or treat cardiovascular disease, such as atherosclerosis.

Cette invention traite de peptides comprenant une partie de déterminant antigénique de lymphocyte T auxiliaire et une partie de déterminant antigénique de lymphocyte B auxiliaire visant à induire une réponse immunitaire dirigée contre une activité de la protéine de transfert d'esters de cholestéryle (CETP), afin de prévenir ou de traiter une maladie cardio-vasculaire telle qu'une athérosclérose.

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