A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) C07K 16/00 (2006.01) C07K 16/28 (2006.01) C07K 16/40 (2006.01)
Patent
CA 2343220
A method of modulating angiogenesis in a vertebrate subject, the method comprising administering to the vertebrate subject an ECRTP/DEP-1 receptor activity-modulating amount of a composition, whereby an ECRTP/DEP-1 receptor within the vertebrate subject is contacted by the composition; and modulating angiogenesis through the contacting of the ECRTP/DEP-1 receptor with the composition. Optionally, the composition includes a monoclonal antibody which preferentially binds the ECRTP/DEP-1 receptor.
Technique permettant de moduler l'angiogénèse chez un vertébré. Cette technique consiste à administrer au vertébré une composition à dose modulant l'activité du récepteur ECRTP/DEP-1, le récepteur, chez le vertébré, entre en contact avec ladite composition; et à moduler l'angiogénèse par le contact du récepteur ECRTP/DEP-1 avec la composition. Eventuellement, la composition comprend un anticorps monoclonal qui, de préférence, se lie au récepteur ECRTP/DEP-1.
Daniel Thomas O.
Takahashi Takamune
Norton Rose Or S.e.n.c.r.l.,s.r.l./llp
Vanderbilt University
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