Modulation of gene expression in formation of fatty...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2398563

Polynucleotides, polypeptides, kits and methods are provided related to genes regulated by the formation of fatty atherosclerotic lesions, and by administration of a dihydropyridine calcium antagonist, lercanidipine.

La présente invention concerne des polynucléotides, des polypeptides, des nécessaires et des procédés se rapportant à des gènes régulés, d'une part par la formation de lésions athéroscléreuses grasses et d'autre part par l'administration d'un antagoniste du calcium de dihydropyridine, la lercanidipine.

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