Modulation of inflammatory responses by factor xi

Details Modulation of inflammatory responses by factor xi Modulation of inflammatory responses by factor xi

A - Human Necessities

61

K

A61K 31/7088 (2006.01) A61K 31/7115 (2006.01) A61K 31/712 (2006.01) A61K 31/7125 (2006.01)

Patent

CA 2758927

Disclosed herein are antisense compounds and methods for modulating Factor XI and modulating an inflammatory disease, disorder or condition in an individual in need thereof. Inflammatory diseases in an individual such as arthritis and colitis can be ameliorated or prevented with the administration of antisense compounds targeted to Factor XI.

La présente invention concerne des composés antisens et des procédés pour la modulation du Facteur XI et la modulation d'une maladie, d'un trouble ou d'un état inflammatoire chez un sujet qui en a besoin. Des maladies inflammatoires chez un sujet telles que l'arthrite et la colite peuvent être atténuées ou prévenues par l'administration de composés antisens ciblés sur le Facteur XI.

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