Modulation of lc132 (opioid-like) receptor function

Details Modulation of lc132 (opioid-like) receptor function Modulation of lc132 (opioid-like) receptor function

A - Human Necessities

61

K

A61K 38/10 (2006.01) C12Q 1/00 (2006.01) G01N 33/566 (2006.01) G01N 33/94 (2006.01)

Patent

CA 2206192

The present invention relates to a method of screening for a therapeutically useful compound which comprises testing an LC132 receptor agonist in a screening assay for psychiatric and/or neurological disorders. Moreparticularly, the screening method is based on contacting an LC132 receptor with an agent suspected of being an agonist of the LC132 receptor function, followed by the detection of the binding and/or the agonist activity of the compound and then testing of an agent with LC132 agonist activity in an antiepileptic, anticonvulsant or anxiolytic screening assay.

La présente invention porte sur une méthode de détection pour un composé utile sur le plan thérapeutique, qui comprend le criblage de l'agoniste du récepteur LC132 dans le cas de troubles psychiatriques et/ou neurologiques. Plus particulièrement, la méthode de criblage consiste à mettre en contact un récepteur LC132 avec un agent présumé être un agoniste du récepteur LC132, puis à détecter la liaison et/ou de l'activité agoniste du composé et à déterminer ensuite si l'agent a une activité agoniste LC132 au moyen du criblage d'un antiépileptique, d'un anticonvulsivant ou d'un anxyolitique.

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