Modulation of lysophosphatidylcholine and treatment of...

Details Modulation of lysophosphatidylcholine and treatment of... Modulation of lysophosphatidylcholine and treatment of...

A - Human Necessities

61

K

A61K 39/395 (2006.01) A01N 37/00 (2006.01) A61K 31/70 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2565387

The present invention provides methods for the treatment of lysophosphatidylcholine-related conditions. In particular, the invention provides a method of treating an insulin-related condition, e.g., diabetes or diabetes type 2, and/or a weight-related-condition, e.g., unwanted weight gain or obesity, in an animal subject by reducing production, absorption and/or activity of lysophosphatidylcholine. Further, the beneficial effects of reducing lysophosphatidylcholine in terms of diabetes and weight gain are disclosed.

Cette invention concerne des procédés pour le traitement des états liés à la lysophosphatidylcholine et en particulier à un procédé pour le traitement d'un état lié à l'insuline, tel que le diabète insulino-dépendant ou le diabète non insulino-dépendant, et/ou d'un état lié au poids, tel qu'une prise de poids non désiré ou l'obésité, chez un sujet animal, grâce à la réduction de la production, de l'absorption et/ou de l'activité de la lysophosphatidylcholine. Les effets bénéfiques de la réduction de lysophosphatidylcholine sur le diabète et la prise de poids sont en outre décrits.

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