Modulation of meiotic recombination

Details Modulation of meiotic recombination Modulation of meiotic recombination

C - Chemistry, Metallurgy

12

N

C12N 15/90 (2006.01) C12N 15/10 (2006.01) C12N 15/79 (2006.01) C12N 15/82 (2006.01)

Patent

CA 2319247

The invention provides methods of modifying the level of expression or functional activity of factors such as enzymes or structural proteins, alone or in concert, to modify the frequency of meiotic homologous recombination involving the exchange of genetic information between non-sister chromatids from homologous maternal and paternal chromosomes. The steps at which modulation may occur include: double strand break formation; resection; strand invasion; and resolution. Methods of plant and animal breeding are also provided that utilize the modulaton of meiotic homologous recombination.

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