A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/195 (2006.01)
Patent
CA 2466800
Provided are methods and compositions for controlling postnatal ocular growth and the development of ocular errors in the maturing eye of a subject, comprising altering the refraction and/or growth of the maturing eye of a subject by administering to the eye a therapeutically effective amount of at least one GABA drug or compound, including agonists or antagonists (alone or in combination with other compounds), as well as any other drug or composition, regardless of classification, that acts to alter the refractive development and/or growth of the eye. Further provided are methods and compositions for treating or preventing myopia, hyperopia or amblyopia.
L'invention concerne des méthodes et de compositions permettant de réguler la croissance oculaire post-natale et de prévenir l'apparition de défauts oculaires au cours de la maturation de l'oeil d'un sujet. Ces méthodes consistent à modifier la réfraction et/ou la croissance de l'oeil en voie de maturation en administrant à cet oeil une dose thérapeutiquement efficace d'au moins un médicament ou un composé modifiant le taux de GABA, notamment des agonistes ou des antagonistes (seuls ou combinés à d'autres composés), ainsi que tout autre médicament ou composition, appartenant à une classification quelconque, qui agit de manière à modifier le développement de la réfraction et/ou la croissance de l'oeil. L'invention concerne en outre de méthodes et des compositions permettant de traiter ou de prévenir la myopie, l'hypermétropie ou l'amblyopie.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
The Trustees Of The University Of Pennsylvania
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