C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/00 (2006.01) A61K 31/7088 (2006.01) A61P 37/02 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2407942
The invention provides methods for modulating the immune response caused by CpG dinucleotide-containing compounds. The methods according to the invention enable both decreasing the immunostimulatory effect for antisense applications, as well as increasing the immunostimulatory effect for immunotherapy applications.
L'invention concerne des méthodes de modulation de la réponse immunitaire engendrée par des composés renfermant le dinucléotide CpG. Selon l'invention, ces méthodes permettent à la fois de diminuer l'effet immunostimulatoire des applications antisens, ainsi que d'accroître l'effet immunostimulatoire dans le cadre d'applications en immunothérapie.
Agrawal Sudhir
Kandimalla Ekambar
Hybridon Inc.
Idera Pharmaceuticals Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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