Modulation of ovulation

Details Modulation of ovulation Modulation of ovulation

C - Chemistry, Metallurgy

07

K

C07K 14/475 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/18 (2006.01) A61K 39/395 (2006.01) A61P 15/08 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/495 (2006.01) C07K 16/22 (2006.01)

Patent

CA 2590419

This invention is directed to novel binding domains of functional significance in GDF-9 and GDF-9B molecules and to agonists and antagonists which interact therewith to modulate the biological activity of these molecules to alter mammalian ovarian function and ovulation rate.

L'invention concerne de nouveaux domaines de liaison d'importance fonctionnelle dans les molécules GDF-9 et GDF-9B, et des agonistes et des antagonistes qui interagissent avec ces domaines pour moduler l'activité biologique de ces molécules et modifier ainsi la fonction ovarienne et le rythme d'ovulation des mammifères.

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