Modulation of peroxisome proliferator-activated receptors

A - Human Necessities – 61 – K

Patent

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A61K 31/37 (2006.01) A61K 31/12 (2006.01) A61K 31/352 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) C12Q 1/26 (2006.01)

Patent

CA 2507738

A method of treating a peroxisome proliferators-activated receptors related disease by administering to a subject in need thereof an effective amount of a modulator of 15-keto prostaglandin-.DELTA.13-reductase. Also disclosed are methods of identifying a compound for inhibiting activity of the reductase and of lowering blood glucose levels by administering to a subject an effective amount of a reductase inhibitor.

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