Modulation of plant cyclin-dependent kinase inhibitor activity

C - Chemistry – Metallurgy – 12 – N

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C12N 15/82 (2006.01) A01H 5/00 (2006.01)

Patent

CA 2433048

In various aspects, the invention provides methods of modifying plant development using cyclin-dependent kinase (CDK) inhibitors, cyclins and proteins that bind to CDK inhibitors, including methods of genetic modification utilizing nucleic acids encoding such proteins. In alternative aspects, the invention may provide methods of plant breeding that facilitate the modulation of plant phenotype in alternative generations. The invention may also provide plants produced by the methods of the invention, including transgenic plants having recombinant genomes that include heterologous sequences encoding CDK inhibitors, cyclins and proteins that bind to CDK inhibitors.

Selon divers aspects, l'invention concerne des procédés qui permettent de modifier la croissance végétale par le biais d'inhibiteurs de CDK, de cyclines et de protéines assurant la liaison avec les inhibiteurs de ce type de kinase, y compris des procédés relatifs à la modification génétique faisant appel à des acides nucléiques qui codent les protéines considérées. Selon d'autres aspects, l'invention concerne différents procédés de sélection des plantes qui facilitent la modulation du phénotype végétal dans les générations alternatives. L'invention concerne également des plantes produites selon les procédés décrits, y compris les plantes transgéniques à génomes de recombinaison qui englobent des séquences hétérologues codant les inhibiteurs de CDK, des cyclines, et des protéines assurant la liaison avec les inhibiteurs de CDK.

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