Modulation of stem cells using zinc finger proteins

Details Modulation of stem cells using zinc finger proteins Modulation of stem cells using zinc finger proteins

A - Human Necessities

61

K

A61K 35/12 (2006.01) C12N 5/071 (2010.01) A01N 37/18 (2006.01) A61K 38/17 (2006.01) A61K 38/18 (2006.01) A61K 38/19 (2006.01) A61P 35/00 (2006.01) C12N 15/63 (2006.01) C12Q 1/02 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2461290

Methods and compositions for modifying stem cells using one or more ZFPs are disclosed. Such methods and compositions are useful for facilitating processes such as, for example, dedifferentiating cells, differentiating stems cells into the desired phenotype, propagating stem cells and/or facilitating cloning.

L'invention concerne des procédés et des compositions permettant de modifier des cellules souches au moyen d'une ou de plusieurs ZFP. De tels procédés et compositions sont utiles pour faciliter des procédés tels que, par exemple, la dédifférenciation cellulaire, la différentiation de cellules souches dans le phénotype souhaité, la propagation de cellules souches et/ou pour faciliter le clonage.

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